氯磷酸二钠脂质体 Clophosome®-氯弗 liposomes
来源:    发布时间: 2015-05-27 20:24   335 次浏览   大小:  16px  14px  12px
品牌:

品牌: liposomes
CAS号: 22560-50-5
供应商: 上海伟进生物科技有限公司    联系人:刘香港 点击这里给我发消息   
数量: 现货
保质期: 6个月
保存条件: 4℃
规格: 2ml/10ml
规格: 2ml 产品价格: ¥2985
规格: 10ml 产品价格: ¥10485

Product Description

Clophosome ® Clodronate Liposomes (Neutral)

Clophosome ®, neutral clodronate liposomes, offers highly efficient in vivo macrophage depletion. Clodronate molecules are encapsulated in small MLV liposomes for superior activity, physical and chemical stability, and convenience of use. It is formulated to an exceptionally high clodronate/lipid ratio. Free clodronate is cleaned out and the liposomal clodronate encapsulation efficiency is more than 90%. Clophosome liposomes remain homogenous and suspended even after long term storage in fridge. It is not viscous and easy to inject. It is manufactured sterile for long term shelf-life. 

The product is suitable for dosing with various routes including intravenous, intraperitoneal, subcutaneous, intranasal, intratracheal and etc.  We have achieved 80-90% macrophage depletion in spleen (red pulp macrophages) 24 hours after a single 0.2 mL intravenous injection.  A starting dose of 0.15 - 0.2 mL (i.v. or i.p.) for 20-25g  animal body weight is recommended for good consistency in macrophage depletion. Optimization is recommended for your specific applications.

 

Specifications

Product code: F70101C-N  

Brand Name : Clophosome ®

Active: clodronate disodium. CAS: 22560-50-5, 7 mg/mL

 

clodronate-disodium.jpg

Lipid composition:   phosphatidylcholine and cholesterol

Bulk solution:   phosphate buffered sucrose (20mM sodium phosphate, 10 % sucrose), pH 7.0-7.5

Shelf-life: 6 months guaranteed for unopened vials

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